Q-omics provides the consensus-scored TULP3 profile across patient tissues and cancer cell-line models. TULP3 expression is associated with patient survival in 21 of 34 cancer types, with the highest sampling consensus in MESO. Among the 18 cancer types available for tumor–normal comparison, TULP3 is differentially expressed in 13, with the highest sampling consensus in KIRC. Additionally, TULP3 RNA expression shows 20,636 significant gene co-expression associations, with the highest sampling consensus in ACC. Together, these results highlight MESO, KIRC, and ACC as cancer lineages where TULP3 shows reproducible signals across survival, tumor–normal expression, and patient cross-omics analyses.
Every result is evaluated using two consensus scores. Sampling consensus measures how consistently a finding is reproduced within a cancer lineage across different conditions. Lineage consensus measures how broadly the result is shared across cancer types, distinguishing pan-cancer signals from lineage-specific patterns.
Premium analyses for TULP3 — synthetic lethality, tumor antigen, and pembrolizumab response.
This table summarizes TULP3 survival associations across molecular data types. TULP3 RNA expression shows survival associations in the most cancer types (21), followed by mutation status (4) and mass-spec protein abundance (4). The rightmost column indicates the cancer type with the highest sampling consensus for each molecular layer.
This table ranks reproducible TULP3 RNA expression–survival associations across cancer types. High TULP3 expression shows unfavorable associations in MESO, ACC, LIHC, BLCA and LGG, but favorable associations in UCEC. The MESO Kaplan–Meier curve shows clear separation, with the high-expression group declining faster, consistent with the unfavorable association (log-rank p < 0.001). Together, the overview and detailed table identify MESO as the clearest survival context for TULP3 RNA expression.
This table summarizes TULP3 tumor–normal expression differences by data type. RNA shows broader differences across cancer types, with a lineage consensus of 13, while mass-spec protein shows differences in 3. The strongest signals are observed in KIRC for RNA and CCRCC for protein.
This table ranks reproducible tumor–normal expression differences for TULP3. A negative fold-change indicates higher expression in normal tissue than in tumor tissue. TULP3 shows lower tumor expression in KICH and higher tumor expression in KIRC, COAD, LIHC, BLCA and KIRP. The KIRC box plot shows higher TULP3 RNA expression in tumor versus normal tissue (log2 FC = +0.733, t-test p < 0.001).
This table shows molecular features associated with TULP3 in patient tissues and cancer cell lines. In patient samples, TULP3 shows the broadest associations at the RNA and protein expression levels, with ACC recurring as the lineage with the largest associated feature set. In cancer cell lines, TULP3 RNA and mutation anchors are most strongly linked to RNA-expression features, especially in LUNG_NSCLC_LUAD, while CRISPR and shRNA rows add functional-dependency signals in BLOOD_Leukemia and CNS.
