TULP3

Across TCGA pan-cancer cohorts, TULP3 mass-spec protein is linked to patient survival in 4 of 34 cancer types, making it a survival-associated TULP3 data layer compared with 21 for mass-spec protein and 4 for mutation status.

The strongest signal is observed in uterine corpus endometrial carcinoma (UCEC), where higher TULP3 mass-spec protein is associated with worse overall survival. In most high-consensus cancer types, elevated TULP3 expression acts as an unfavorable survival marker, although some lineages such as HNSC show a favorable association.

UCEC, CCRCC, and LUAD are the cancer types where TULP3 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
UCEC	OS	Tertile	II,III,IV	0.500	1.000	.015	20	view →
CCRCC	DFS	Tertile	All	0.627	0.835	.017	5	view →
LUAD	DFS	Median	III,IV	0.432	0.925	.047	4	view →
HNSC	OS	Tertile	II,III,IV	0.853	0.599	.023	4	view →

Pink = unfavorable, green = favorable. Showing the 4 strongest of 4 lineages.

TULP3–UCEC (OS)

Open the UCEC breakdown →