TULP3

Across TCGA pan-cancer cohorts, TULP3 RNA differs between tumor and matched normal tissue in 13 of 18 cancer types tested, making tumor–normal expression one of TULP3’s most consistent transcriptional readouts.

The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where TULP3 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types TULP3 is over-expressed in tumor, although a few such as KICH and THCA show the opposite, repressed pattern.

KIRC, COAD, and LIHC are the cancer types where TULP3 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in TULP3 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
KIRC	Female	III,IV	+0.733	<.001	12	view →
COAD	Male	IV	+1.208	<.001	11	view →
LIHC	Female	II,III,IV	+1.355	<.001	9	view →
BLCA	All	All	+0.574	<.001	9	view →
KIRP	All	All	+0.526	.002	9	view →
KICH	Female	II,III,IV	−1.799	<.001	8	view →
HNSC	All	All	+0.642	<.001	7	view →
LUSC	Female	All	+0.819	<.001	6	view →
LUAD	All	II,III,IV	+0.404	.001	6	view →
CHOL	Female	All	+3.329	<.001	5	view →
THCA	All	II,III,IV	−0.435	.003	4	view →
READ	Male	All	+1.473	.044	3	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 12 strongest of 13 lineages.

TULP3–KIRC

Open the KIRC breakdown →