TULP3

Across TCGA pan-cancer cohorts, TULP3 RNA is linked to patient survival in 21 of 34 cancer types, making it the most broadly survival-associated TULP3 data layer compared with 4 for mutation status and 4 for mass-spec protein.

The strongest signal is observed in mesothelioma (MESO), where higher TULP3 RNA is associated with worse overall survival. In most high-consensus cancer types, elevated TULP3 expression acts as an unfavorable survival marker, although some lineages such as UCEC and HNSC show a favorable association.

MESO, ACC, and UCEC are the cancer types where TULP3 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
MESO	OS	Median	All	0.263	0.503	<.001	111	view →
ACC	DFS	Median	All	0.418	0.744	<.001	108	view →
UCEC	DFS	Tertile	IV	0.824	0.323	.006	76	view →
LIHC	DFS	Median	All	0.459	0.619	<.001	70	view →
BLCA	DFS	Tertile	All	0.253	0.458	.001	68	view →
LGG	OS	Median	All	0.346	0.569	<.001	53	view →
HNSC	DFS	Quartile	IV	0.817	0.556	.001	38	view →
KIRC	DFS	Median	All	0.718	0.537	.016	22	view →
SARC	DFS	Median	All	0.271	0.414	.010	15	view →
KICH	OS	Median	III,IV	0.378	0.894	.016	14	view →
READ	OS	Tertile	IV	1.000	0.611	.021	14	view →
SKCM	OS	Median	All	0.311	0.484	.012	12	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 21 lineages.

TULP3–MESO (OS)

Open the MESO breakdown →