TULP3

Across TCGA pan-cancer cohorts, TULP3 Mutation is linked to patient survival in 4 of 34 cancer types, making it a survival-associated TULP3 data layer compared with 21 for mass-spec protein and 4 for mass-spec protein.

The strongest signal is observed in bladder urothelial carcinoma (BLCA), where higher TULP3 Mutation is associated with worse disease-free survival. In most high-consensus cancer types, elevated TULP3 expression acts as an unfavorable survival marker.

BLCA, THYM, and LUAD are the cancer types where TULP3 Mutation most reproducibly stratifies survival.

Mutation survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
BLCA	DFS	Median	III,IV	0.083	0.572	<.001	15	view →
THYM	OS	Median	All	0.352	0.884	<.001	8	view →
LUAD	DFS	Median	II,III,IV	0.098	0.682	<.001	6	view →
LIHC	OS	Median	II,III,IV	0.255	0.768	.018	3	view →

Pink = unfavorable, green = favorable. Showing the 4 strongest of 4 lineages.

TULP3–BLCA (DFS)

Open the BLCA breakdown →