striatin interacting protein 1Genealiases: FAM40A · FAR11A
Q-omics provides the consensus-scored STRIP1 profile across patient tissues and cancer cell-line models. STRIP1 expression is associated with patient survival in 21 of 34 cancer types, with the highest sampling consensus in ACC. Among the 18 cancer types available for tumor–normal comparison, STRIP1 is differentially expressed in 10, with the highest sampling consensus in LIHC. Additionally, STRIP1 RNA expression shows 20,096 significant gene co-expression associations, with the highest sampling consensus in ACC. Together, these results highlight ACC, and LIHC as cancer lineages where STRIP1 shows reproducible signals across survival, tumor–normal expression, and patient cross-omics analyses.
Every result is evaluated using two consensus scores. Sampling consensus measures how consistently a finding is reproduced within a cancer lineage across different conditions. Lineage consensus measures how broadly the result is shared across cancer types, distinguishing pan-cancer signals from lineage-specific patterns.
Premium analyses for STRIP1 — synthetic lethality, tumor antigen, and pembrolizumab response.
This table summarizes STRIP1 survival associations across molecular data types. STRIP1 RNA expression shows survival associations in the most cancer types (21), followed by mutation status (2) and mass-spec protein abundance (5). The rightmost column indicates the cancer type with the highest sampling consensus for each molecular layer.
This table ranks reproducible STRIP1 RNA expression–survival associations across cancer types. High STRIP1 expression shows unfavorable associations in ACC, LIHC, LGG and LUSC, but favorable associations in BRCA and READ. The ACC Kaplan–Meier curve shows clear separation, with the high-expression group declining faster, consistent with the unfavorable association (log-rank p < 0.001). Together, the overview and detailed table identify ACC as the clearest survival context for STRIP1 RNA expression.
This table summarizes STRIP1 tumor–normal expression differences by data type. RNA shows broader differences across cancer types, with a lineage consensus of 10, while mass-spec protein shows differences in 5. The strongest signals are observed in LIHC for RNA and COAD for protein.
This table ranks reproducible tumor–normal expression differences for STRIP1. A negative fold-change indicates higher expression in normal tissue than in tumor tissue. STRIP1 shows lower tumor expression in KICH, UCEC and BRCA and higher tumor expression in LIHC, CHOL and BLCA. The LIHC box plot shows higher STRIP1 RNA expression in tumor versus normal tissue (log2 FC = +1.032, t-test p < 0.001).
This table shows molecular features associated with STRIP1 in patient tissues and cancer cell lines. In patient samples, STRIP1 shows the broadest associations at the RNA and protein expression levels, with ACC recurring as the lineage with the largest associated feature set. In cancer cell lines, STRIP1 RNA and mutation anchors are most strongly linked to RNA-expression features, especially in UPPER_AERODIGESTIVE_TRACT, while CRISPR and shRNA rows add functional-dependency signals in CNS and BLOOD_Leukemia.
