STRIP1

Across TCGA patient cohorts, STRIP1 mutation is significantly associated with the RNA expression of many other genes, with 3,401 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible STRIP1-associated genes across cancer lineages are MIR6133, RN7SKP263, and RNU6-890P. Each is linked with STRIP1 in more than 1 cancer types. Because this analysis shows association rather than direction, both STRIP1-to-partner and partner-to-STRIP1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MIR6133 grouped by STRIP1-low versus STRIP1-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (STRIP1→partner) and Y-score (partner→STRIP1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	MIR6133 →	+0.231	+2.330	.002	<.001	3	2
CESC	RN7SKP263 →	+0.098	+4.984	<.001	.003	3	2
BLCA	RNU6-890P →	+0.677	+3.643	.002	.008	3	2
UCEC	FANCM →	+0.309	+3.385	.005	.004	3	2
UCEC	ERI2 →	+0.411	+2.247	.001	.001	3	2
UCEC	MCMBP →	+0.500	+2.697	<.001	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,401 associations by consensus.

MIR6133 by STRIP1 expression — UCEC

Explore this box plot interactively →