STRIP1

Across TCGA cell cohorts, STRIP1 mutation is significantly associated with the RNA expression of many other genes, with 16 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible STRIP1-associated genes across cancer lineages are MYH1, GML, and HHLA1. Each is linked with STRIP1 in more than 1 cancer types. Because this analysis shows association rather than direction, both STRIP1-to-partner and partner-to-STRIP1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MYH1 grouped by STRIP1-low versus STRIP1-high in LUNG_NSCLC_LUAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (STRIP1→partner) and Y-score (partner→STRIP1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUAD	MYH1 →	+0.012	+4.662	<.001	.005	3	1
BLOOD_Leukemia	GML →	+0.062	+4.152	.003	.009	3	1
BLOOD_Leukemia	HHLA1 →	+0.011	+4.551	<.001	.004	3	1
BLOOD_Leukemia	ASZ1 →	+0.137	+4.152	<.001	.009	3	1
BLOOD_Leukemia	RXFP3 →	+0.018	+4.874	<.001	.002	3	1
BLOOD_Leukemia	OR1D4 →	+0.046	+4.539	<.001	.007	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 16 associations by consensus.

MYH1 by STRIP1 expression — LUNG_NSCLC_LUAD

Explore this box plot interactively →