STRIP1

Across TCGA pan-cancer cohorts, STRIP1 mass-spec protein is linked to patient survival in 5 of 34 cancer types, making it a survival-associated STRIP1 data layer compared with 21 for mass-spec protein and 2 for mutation status.

The strongest signal is observed in head and neck squamous cell carcinoma (HNSC), where higher STRIP1 mass-spec protein is associated with better overall survival. In most high-consensus cancer types, elevated STRIP1 expression acts as an unfavorable survival marker, although some lineages such as HNSC and PDAC show a favorable association.

HNSC, PDAC, and GBM are the cancer types where STRIP1 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
HNSC	OS	Tertile	III,IV	0.993	0.744	.003	62	view →
PDAC	DFS	Tertile	III,IV	0.982	0.352	.002	28	view →
GBM	OS	Median	All	0.535	0.301	.022	3	view →
LUAD	DFS	Median	III,IV	0.314	0.693	.044	2	view →
CCRCC	DFS	Quartile	III,IV	0.751	0.339	.047	2	view →

Pink = unfavorable, green = favorable. Showing the 5 strongest of 5 lineages.

STRIP1–HNSC (OS)

Open the HNSC breakdown →