STRIP1

Across TCGA cell cohorts, STRIP1 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,214 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible STRIP1-associated GO terms across cancer lineages are Negative regulation of gene expression, epigenetic, Positive regulation of organelle assembly, and Heterochromatin formation. Each is linked with STRIP1 in more than 16 cancer types. Because this analysis shows association rather than direction, both STRIP1-to-partner and partner-to-STRIP1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Negative regulation of gene expression, epigenetic grouped by STRIP1-low versus STRIP1-high in LARGE_INTESTINE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (STRIP1→partner) and Y-score (partner→STRIP1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	Negative regulation of gene expression, epigenetic →	+0.067	+0.775	<.001	<.001	3	17
STOMACH	Positive regulation of organelle assembly →	+0.069	+0.841	<.001	<.001	3	17
STOMACH	Heterochromatin formation →	+0.071	+0.719	.001	.003	3	17
LARGE_INTESTINE	Microtubule polymerization →	+0.112	+0.761	<.001	<.001	3	16
LARGE_INTESTINE	Microtubule nucleation →	+0.114	+0.777	<.001	<.001	3	16
BONE	Regulation of RNA splicing →	+0.090	+0.774	.001	.001	3	15

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,214 associations by consensus.

Negative regulation of gene expression, epigenetic by STRIP1 expression — LARGE_INTESTINE

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