C22orf31

Q-omics provides the consensus-scored C22orf31 profile across patient tissues and cancer cell-line models. C22orf31 expression is associated with patient survival in 1 of 34 cancer types, with the highest sampling consensus in SCLC. Additionally, C22orf31 RNA expression shows 10,222 significant protein co-abundance associations, with the highest sampling consensus in HNSC. Together, these results highlight SCLC, and HNSC as cancer lineages where C22orf31 shows reproducible signals across survival, tumor–normal expression, and patient cross-omics analyses.

Every result is evaluated using two consensus scores. Sampling consensus measures how consistently a finding is reproduced within a cancer lineage across different conditions. Lineage consensus measures how broadly the result is shared across cancer types, distinguishing pan-cancer signals from lineage-specific patterns.

Survival associations

This table summarizes C22orf31 survival associations across molecular data types. C22orf31 RNA expression shows survival associations in the most cancer types (1), followed by mutation status (6) and mass-spec protein abundance (1). The rightmost column indicates the cancer type with the highest sampling consensus for each molecular layer.

C22orf31 data type	Survival analysis	Lineage consensus	Lineage of highest sampling consensus
Mutation	Kaplan–Meier	6	SCLC (48)	view →
Protein (mass-spec)	Kaplan–Meier	1	LUAD (5)	view →
RNA	Kaplan–Meier	1	SCLC (13)	view →

This table ranks reproducible C22orf31 RNA expression–survival associations across cancer types. High C22orf31 expression shows unfavorable associations in SCLC. The SCLC Kaplan–Meier curve shows clear separation, with the high-expression group declining faster, consistent with the unfavorable association (log-rank p = .002). Together, the overview and detailed table identify SCLC as the clearest survival context for C22orf31 RNA expression.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
SCLC	DFS	Quartile	III,IV	0.251	0.666	.002	13	view →

Pink = unfavorable, green = favorable. all 1 lineages →

C22orf31-SCLC (DFS)

Explore this curve interactively →