C22orf31

Across TCGA pan-cancer cohorts, C22orf31 mass-spec protein is linked to patient survival in 1 of 34 cancer types, making it a survival-associated C22orf31 data layer compared with 1 for mass-spec protein and 6 for mutation status.

The strongest signal is observed in lung adenocarcinoma (LUAD), where higher C22orf31 mass-spec protein is associated with better disease-free survival. In most high-consensus cancer types, elevated C22orf31 expression acts as an unfavorable survival marker, although some lineages such as LUAD show a favorable association.

LUAD are the cancer types where C22orf31 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
LUAD	DFS	Median	All	0.852	0.287	.024	5	view →

Pink = unfavorable, green = favorable. Showing the 1 strongest of 1 lineages.

C22orf31–LUAD (DFS)

Open the LUAD breakdown →