C22orf31

Across TCGA cell cohorts, C22orf31 RNA expression is significantly associated with the RNA expression of many other genes, with 1,609 significant associations in total. SOFT_TISSUE shows the largest number of these associations.

The most reproducible C22orf31-associated genes across cancer lineages are KREMEN1, CLDN17, and ALOX15. Each is linked with C22orf31 in more than 2 cancer types. Because this analysis shows association rather than direction, both C22orf31-to-partner and partner-to-C22orf31 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, C22orf31 versus KREMEN1 in LARGE_INTESTINE, with a Pearson correlation of 0.66.

RNA expression associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (C22orf31→partner) and Y-score (partner→C22orf31) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	KREMEN1 →	+2.433	+0.244	<.001	.003	3	3
CNS	CLDN17 →	+0.034	+0.050	.009	<.001	3	3
SOFT_TISSUE	ALOX15 →	+1.709	+0.202	<.001	<.001	3	2
SOFT_TISSUE	PROP1 →	+0.043	+0.227	.003	<.001	3	2
BONE	AKAIN1 →	+0.119	+0.139	.004	<.001	3	2
BLOOD_Lymphoma	PYDC1 →	+0.195	+0.009	.005	.002	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,609 associations by consensus.

C22orf31 vs KREMEN1 — LARGE_INTESTINE

Explore this scatter interactively →