Q-omics provides the consensus-scored KREMEN1 profile across patient tissues and cancer cell-line models. KREMEN1 expression is associated with patient survival in 1 of 34 cancer types, with the highest sampling consensus in SCLC. Additionally, KREMEN1 RNA expression shows 13,993 significant protein co-abundance associations, with the highest sampling consensus in LSCC. Together, these results highlight SCLC, and LSCC as cancer lineages where KREMEN1 shows reproducible signals across survival, tumor–normal expression, and patient cross-omics analyses.

Every result is evaluated using two consensus scores. Sampling consensus measures how consistently a finding is reproduced within a cancer lineage across different conditions. Lineage consensus measures how broadly the result is shared across cancer types, distinguishing pan-cancer signals from lineage-specific patterns.

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Survival associations

This table summarizes KREMEN1 survival associations across molecular data types. KREMEN1 RNA expression shows survival associations in the most cancer types (1), followed by mutation status (5) and mass-spec protein abundance (3). The rightmost column indicates the cancer type with the highest sampling consensus for each molecular layer.

KREMEN1 data type	Survival analysis	Lineage consensus	Lineage of highest sampling consensus
Mutation	Kaplan–Meier	5	LUSC (14)	view →
Protein (mass-spec)	Kaplan–Meier	3	LUAD (3)	view →
RNA	Kaplan–Meier	1	SCLC (4)	view →

This table ranks reproducible KREMEN1 RNA expression–survival associations across cancer types. High KREMEN1 expression shows favorable associations in SCLC. The SCLC Kaplan–Meier curve shows clear separation, with the low-expression group declining faster, consistent with the favorable association (log-rank p = .024). Together, the overview and detailed table identify SCLC as the clearest survival context for KREMEN1 RNA expression.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
SCLC	DFS	Quartile	II,III,IV	0.852	0.269	.024	4	view →

Pink = unfavorable, green = favorable. all 1 lineages →

KREMEN1-SCLC (DFS)

Kaplan–Meier survival curve for KREMEN1 RNA expression in SCLC: high vs low expression groups.

Explore this curve interactively →

Cross-omics associations

This table shows molecular features associated with KREMEN1 in patient tissues and cancer cell lines. In patient samples, KREMEN1 shows the broadest associations at the RNA and protein expression levels, with LSCC recurring as the lineage with the largest associated feature set. In cancer cell lines, KREMEN1 RNA and mutation anchors are most strongly linked to RNA-expression features, especially in UPPER_AERODIGESTIVE_TRACT, while CRISPR and shRNA rows add functional-dependency signals in CNS and LARGE_INTESTINE.

Associated data type	Strength (# associated data)	Lineage of highest associated data
▼RNA
Protein (mass-spec)	13,993	LSCC (5144)	view →
RNA	2,371	SCLC (2371)	view →
▼Mutation
RNA	2,959	UCEC (2858)	view →
Protein (RPPA)	15	UCEC (15)	view →
▼Protein (mass-spec)
Protein (mass-spec)	2,274	LSCC (598)	view →
RNA	625	GBM (204)	view →

Associated data type	Strength (# associated data)	Lineage of highest associated data
▼CRISPR
RNA	2,152	UPPER_AERODIGESTIVE_TRACT (463)	view →
CRISPR	1,880	CNS (126)	view →
▼RNA
RNA	10,615	LARGE_INTESTINE (3142)	view →
Function (RNA)	4,344	SOFT_TISSUE (885)	view →
▼Mutation
Mutation	1,669	BLOOD_Leukemia (1324)	view →
RNA	12	SKIN (7)	view →
▼shRNA
RNA	1,503	LUNG_SCLC (229)	view →
shRNA	1,399	BREAST (139)	view →