Across TCGA patient cohorts, KREMEN1 protein abundance is significantly associated with the RNA expression of many other genes, with 625 significant associations in total. GBM shows the largest number of these associations.

The most reproducible KREMEN1-associated genes across cancer lineages are IRAK2, LYRM1, and CPP. Each is linked with KREMEN1 in more than 1 cancer types. Because this analysis shows association rather than direction, both KREMEN1-to-partner and partner-to-KREMEN1 results are reported.

Each partner links to its own Q-omics profile.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (KREMEN1→partner) and Y-score (partner→KREMEN1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	IRAK2 →	+1.001	+0.350	.004	<.001	3	2
LUAD	LYRM1 →	-0.582	-0.463	.002	.004	3	2
BRCA	CPP →	+1.147	+1.282	.001	.004	3	2
UCEC	SQLE →	-0.593	-0.777	.009	.002	3	1
UCEC	TGFB1 →	+1.016	+0.900	.009	.005	3	1
UCEC	CEACAM4 →	+0.956	+1.104	.002	<.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 625 associations by consensus.

Exploration

KREMEN1 survival (RNA) · tumor vs normal (RNA) · all KREMEN1 data types