C22orf31

Across TCGA patient cohorts, C22orf31 RNA expression is significantly associated with the protein abundance of many other proteins, with 10,222 significant associations in total. HNSC shows the largest number of these associations.

The most reproducible C22orf31-associated proteins across cancer lineages are TRIM2, PSPH, and NRCAM. Each is linked with C22orf31 in more than 3 cancer types. Because this analysis shows association rather than direction, both C22orf31-to-partner and partner-to-C22orf31 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, C22orf31 versus TRIM2 in HNSC, with a Pearson correlation of 0.35.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (C22orf31→partner) and Y-score (partner→C22orf31) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	TRIM2 →	+0.435	+0.501	<.001	<.001	3	4
HNSC	PSPH →	+0.602	+0.556	<.001	.002	3	3
HNSC	NRCAM →	+0.852	+0.695	<.001	.002	3	3
UCEC	PKP4 →	+0.314	+0.557	<.001	<.001	2	4
HNSC	ARHGEF10L →	-0.399	-0.597	<.001	<.001	3	3
COAD	CTSL →	-0.415	-0.169	.002	.003	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 10,222 associations by consensus.

C22orf31 vs TRIM2 — HNSC

Explore this scatter interactively →