C22orf31

Across TCGA patient cohorts, C22orf31 protein abundance is significantly associated with the RNA expression of many other genes, with 343 significant associations in total. CCRCC shows the largest number of these associations.

The most reproducible C22orf31-associated genes across cancer lineages are UBR5, PUS3, and GALNT18. Each is linked with C22orf31 in more than 1 cancer types. Because this analysis shows association rather than direction, both C22orf31-to-partner and partner-to-C22orf31 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, C22orf31 versus UBR5 in GBM, with a Pearson correlation of -0.55.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (C22orf31→partner) and Y-score (partner→C22orf31) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	UBR5 →	-0.264	-0.364	<.001	<.001	3	1
GBM	PUS3 →	-0.367	-0.344	.003	.006	3	1
GBM	GALNT18 →	+0.635	+0.325	.009	.005	3	1
GBM	CLINT1 →	-0.204	-0.323	<.001	.001	3	1
GBM	GORASP2 →	-0.376	-0.420	.005	<.001	3	1
GBM	CAPRIN1 →	-0.375	-0.408	<.001	.003	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 343 associations by consensus.

C22orf31 vs UBR5 — GBM

Explore this scatter interactively →