Q-omics provides the consensus-scored WDR24 profile across patient tissues and cancer cell-line models. WDR24 expression is associated with patient survival in 21 of 34 cancer types, with the highest sampling consensus in COAD. Among the 18 cancer types available for tumor–normal comparison, WDR24 is differentially expressed in 14, with the highest sampling consensus in HNSC. Additionally, WDR24 RNA expression shows 18,373 significant gene co-expression associations, with the highest sampling consensus in ACC. Together, these results highlight COAD, HNSC, and ACC as cancer lineages where WDR24 shows reproducible signals across survival, tumor–normal expression, and patient cross-omics analyses.
Every result is evaluated using two consensus scores. Sampling consensus measures how consistently a finding is reproduced within a cancer lineage across different conditions. Lineage consensus measures how broadly the result is shared across cancer types, distinguishing pan-cancer signals from lineage-specific patterns.
Premium analyses for WDR24 — synthetic lethality, tumor antigen, and pembrolizumab response.
This table summarizes WDR24 survival associations across molecular data types. WDR24 RNA expression shows survival associations in the most cancer types (21), followed by mutation status (4) and mass-spec protein abundance (5). The rightmost column indicates the cancer type with the highest sampling consensus for each molecular layer.
This table ranks reproducible WDR24 RNA expression–survival associations across cancer types. High WDR24 expression shows unfavorable associations in COAD and KIRP, but favorable associations in HNSC, BRCA, CESC and ESCA. The COAD Kaplan–Meier curve shows clear separation, with the high-expression group declining faster, consistent with the unfavorable association (log-rank p < 0.001). Together, the overview and detailed table identify COAD as the clearest survival context for WDR24 RNA expression.
This table summarizes WDR24 tumor–normal expression differences by data type. RNA shows broader differences across cancer types, with a lineage consensus of 14, while mass-spec protein shows differences in 8. The strongest signals are observed in HNSC for RNA and COAD for protein.
This table ranks reproducible tumor–normal expression differences for WDR24. A negative fold-change indicates higher expression in normal tissue than in tumor tissue. WDR24 shows higher tumor expression in HNSC, KIRP, KIRC, COAD, LIHC and STAD. The HNSC box plot shows higher WDR24 RNA expression in tumor versus normal tissue (log2 FC = +0.622, t-test p < 0.001).
This table shows molecular features associated with WDR24 in patient tissues and cancer cell lines. In patient samples, WDR24 shows the broadest associations at the RNA and protein expression levels, with ACC recurring as the lineage with the largest associated feature set. In cancer cell lines, WDR24 RNA and mutation anchors are most strongly linked to RNA-expression features, especially in SKIN, while CRISPR and shRNA rows add functional-dependency signals in BLOOD_Leukemia and LARGE_INTESTINE.
