WDR24

Across TCGA pan-cancer cohorts, WDR24 RNA is linked to patient survival in 21 of 34 cancer types, making it the most broadly survival-associated WDR24 data layer compared with 4 for mutation status and 5 for mass-spec protein.

The strongest signal is observed in colon adenocarcinoma (COAD), where higher WDR24 RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated WDR24 expression acts as an unfavorable survival marker, although some lineages such as HNSC and BRCA show a favorable association.

COAD, HNSC, and BRCA are the cancer types where WDR24 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
COAD	DFS	Median	All	0.351	0.775	<.001	37	view →
HNSC	DFS	Median	III,IV	0.665	0.521	.007	28	view →
BRCA	OS	Median	IV	0.796	0.382	.004	24	view →
ESCA	DFS	Median	All	0.927	0.438	.003	18	view →
CESC	OS	Median	III,IV	0.679	0.238	.018	18	view →
KIRP	DFS	Quartile	IV	0.519	0.894	.024	18	view →
ACC	DFS	Tertile	III,IV	0.555	0.105	.003	15	view →
SCLC	DFS	Tertile	II,III,IV	1.000	0.342	.006	15	view →
READ	OS	Median	IV	0.466	0.824	.006	14	view →
LUAD	DFS	Tertile	IV	0.451	0.886	.022	12	view →
OV	OS	Tertile	IV	0.761	0.513	.023	10	view →
LIHC	DFS	Quartile	All	0.333	0.521	.002	10	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 21 lineages.

WDR24–COAD (DFS)

Open the COAD breakdown →