WDR24

Across TCGA cell cohorts, WDR24 mutation is significantly associated with the RNA expression of many other genes, with 473 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible WDR24-associated genes across cancer lineages are CBY1, C12orf57, and ATF2. Each is linked with WDR24 in more than 1 cancer types. Because this analysis shows association rather than direction, both WDR24-to-partner and partner-to-WDR24 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, CBY1 grouped by WDR24-low versus WDR24-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (WDR24→partner) and Y-score (partner→WDR24) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	CBY1 →	+0.856	+3.299	<.001	.004	3	2
LARGE_INTESTINE	C12orf57 →	+0.856	+3.212	.003	.006	3	2
LARGE_INTESTINE	ATF2 →	+0.460	+3.212	.005	.006	3	2
LARGE_INTESTINE	FEM1A →	+0.564	+3.212	.002	.006	3	2
LARGE_INTESTINE	METTL14 →	+0.597	+3.212	.004	.006	3	2
LARGE_INTESTINE	PKNOX1 →	+0.559	+3.087	.005	.006	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 473 associations by consensus.

CBY1 by WDR24 expression — LARGE_INTESTINE

Explore this box plot interactively →