Q-omics provides the consensus-scored UTS2R profile across patient tissues and cancer cell-line models. UTS2R expression is associated with patient survival in 25 of 34 cancer types, with the highest sampling consensus in HNSC. Among the 18 cancer types available for tumor–normal comparison, UTS2R is differentially expressed in 8, with the highest sampling consensus in THCA. Additionally, UTS2R RNA expression shows 17,348 significant gene co-expression associations, with the highest sampling consensus in THYM. Together, these results highlight HNSC, THCA, and THYM as cancer lineages where UTS2R shows reproducible signals across survival, tumor–normal expression, and patient cross-omics analyses.
Every result is evaluated using two consensus scores. Sampling consensus measures how consistently a finding is reproduced within a cancer lineage across different conditions. Lineage consensus measures how broadly the result is shared across cancer types, distinguishing pan-cancer signals from lineage-specific patterns.
Premium analyses for UTS2R — synthetic lethality, tumor antigen, and pembrolizumab response.
This table summarizes UTS2R survival associations across molecular data types. UTS2R RNA expression shows survival associations in the most cancer types (25), followed by mutation status (4). The rightmost column indicates the cancer type with the highest sampling consensus for each molecular layer.
This table ranks reproducible UTS2R RNA expression–survival associations across cancer types. High UTS2R expression shows unfavorable associations in UVM, ACC and KIRC, but favorable associations in HNSC, SKCM and BRCA. The HNSC Kaplan–Meier curve shows clear separation, with the low-expression group declining faster, consistent with the favorable association (log-rank p < 0.001). Together, the overview and detailed table identify HNSC as the clearest survival context for UTS2R RNA expression.
This table summarizes UTS2R tumor–normal expression differences by data type. RNA shows broader differences across cancer types, with a lineage consensus of 8. The strongest signals are observed in THCA for RNA.
This table ranks reproducible tumor–normal expression differences for UTS2R. A negative fold-change indicates higher expression in normal tissue than in tumor tissue. UTS2R shows lower tumor expression in THCA, KICH, KIRC, BRCA and KIRP and higher tumor expression in LIHC. The THCA box plot shows higher UTS2R RNA expression in normal versus tumor tissue (log2 FC = −2.148, t-test p < 0.001).
This table shows molecular features associated with UTS2R in patient tissues and cancer cell lines. In patient samples, UTS2R shows the broadest associations at the RNA and protein expression levels, with THYM recurring as the lineage with the largest associated feature set. In cancer cell lines, UTS2R RNA and mutation anchors are most strongly linked to RNA-expression features, especially in SKIN, while CRISPR and shRNA rows add functional-dependency signals in SOFT_TISSUE and BLOOD_Leukemia.
