UTS2R

Across TCGA pan-cancer cohorts, UTS2R RNA differs between tumor and matched normal tissue in 8 of 18 cancer types tested, making tumor–normal expression one of UTS2R’s most consistent transcriptional readouts.

The strongest signal is observed in thyroid carcinoma (THCA), where UTS2R RNA is repressed in tumor relative to normal tissue. In most cancer types UTS2R is over-expressed in tumor, although a few such as THCA and KICH show the opposite, repressed pattern.

THCA, KICH, and KIRC are the cancer types where UTS2R tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in UTS2R RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
THCA	All	III,IV	−2.148	<.001	11	view →
KICH	Male	All	−1.601	<.001	10	view →
KIRC	Male	II,III,IV	−0.902	<.001	7	view →
BRCA	Female	II,III,IV	−0.214	<.001	6	view →
KIRP	Male	All	−0.708	.001	4	view →
LIHC	All	All	+0.081	.003	3	view →
STAD	All	IV	−1.006	.002	2	view →
LUAD	Female	All	+0.096	.036	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 8 strongest of 8 lineages.

UTS2R–THCA

Open the THCA breakdown →