UTS2R

Across TCGA cell cohorts, UTS2R mutation is significantly associated with the RNA expression of many other genes, with 10 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible UTS2R-associated genes across cancer lineages are TEX43, TBC1D21, and TACR3. Each is linked with UTS2R in more than 1 cancer types. Because this analysis shows association rather than direction, both UTS2R-to-partner and partner-to-UTS2R results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, TEX43 grouped by UTS2R-low versus UTS2R-high in BLOOD_Leukemia.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (UTS2R→partner) and Y-score (partner→UTS2R) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	TEX43 →	+0.105	+4.969	<.001	.003	3	2
STOMACH	TBC1D21 →	+0.076	+4.129	<.001	.007	3	1
BLOOD_Leukemia	TACR3 →	+0.043	+5.060	<.001	.001	3	1
BLOOD_Leukemia	PRND →	+0.011	+4.874	<.001	.002	3	1
BLOOD_Leukemia	CCT8L2 →	+0.019	+4.874	<.001	.002	3	1
BLOOD_Leukemia	OR1D4 →	+0.046	+4.539	<.001	.007	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 10 associations by consensus.

TEX43 by UTS2R expression — BLOOD_Leukemia

Explore this box plot interactively →