UTS2R

Across TCGA patient cohorts, UTS2R mutation is significantly associated with the RNA expression of many other genes, with 132 significant associations in total. COAD shows the largest number of these associations.

The most reproducible UTS2R-associated genes across cancer lineages are RNA5SP426, RN7SKP261, and MIR4688. Each is linked with UTS2R in more than 1 cancer types. Because this analysis shows association rather than direction, both UTS2R-to-partner and partner-to-UTS2R results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNA5SP426 grouped by UTS2R-low versus UTS2R-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (UTS2R→partner) and Y-score (partner→UTS2R) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	RNA5SP426 →	+0.347	+4.453	<.001	.006	3	2
UCEC	RN7SKP261 →	+0.494	+3.830	.007	.005	3	2
SKCM	MIR4688 →	+0.513	+5.224	<.001	.007	3	2
SKCM	SPINT4 →	+0.114	+5.037	<.001	.009	3	1
UCEC	SNORD116-10 →	+0.359	+4.335	<.001	.007	3	1
UCEC	RNU1-32P →	+0.292	+5.049	<.001	.002	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 132 associations by consensus.

RNA5SP426 by UTS2R expression — UCEC

Explore this box plot interactively →