dipeptidyl peptidase 7Genealiases: DPP · DPP II · DPP2 · DPPII · II · QPP
Q-omics provides the consensus-scored DPP7 profile across patient tissues and cancer cell-line models. DPP7 expression is associated with patient survival in 27 of 34 cancer types, with the highest sampling consensus in COAD. Among the 18 cancer types available for tumor–normal comparison, DPP7 is differentially expressed in 13, with the highest sampling consensus in COAD. Additionally, DPP7 RNA expression shows 18,484 significant gene co-expression associations, with the highest sampling consensus in THYM. Together, these results highlight COAD, and THYM as cancer lineages where DPP7 shows reproducible signals across survival, tumor–normal expression, and patient cross-omics analyses.
Every result is evaluated using two consensus scores. Sampling consensus measures how consistently a finding is reproduced within a cancer lineage across different conditions. Lineage consensus measures how broadly the result is shared across cancer types, distinguishing pan-cancer signals from lineage-specific patterns.
Premium analyses for DPP7 — synthetic lethality, tumor antigen, and pembrolizumab response.
This table summarizes DPP7 survival associations across molecular data types. DPP7 RNA expression shows survival associations in the most cancer types (27), followed by mutation status (5) and mass-spec protein abundance (6). The rightmost column indicates the cancer type with the highest sampling consensus for each molecular layer.
This table ranks reproducible DPP7 RNA expression–survival associations across cancer types. High DPP7 expression shows unfavorable associations in COAD, ACC, UCS, UVM, MESO and LGG. The COAD Kaplan–Meier curve shows clear separation, with the high-expression group declining faster, consistent with the unfavorable association (log-rank p < 0.001). Together, the overview and detailed table identify COAD as the clearest survival context for DPP7 RNA expression.
This table summarizes DPP7 tumor–normal expression differences by data type. RNA shows broader differences across cancer types, with a lineage consensus of 13, while mass-spec protein shows differences in 4. The strongest signals are observed in KIRC for RNA and CCRCC for protein.
This table ranks reproducible tumor–normal expression differences for DPP7. A negative fold-change indicates higher expression in normal tissue than in tumor tissue. DPP7 shows lower tumor expression in LUAD and higher tumor expression in COAD, KIRC, LIHC, KIRP and READ. The COAD box plot shows higher DPP7 RNA expression in tumor versus normal tissue (log2 FC = +1.523, t-test p < 0.001).
This table shows molecular features associated with DPP7 in patient tissues and cancer cell lines. In patient samples, DPP7 shows the broadest associations at the RNA and protein expression levels, with THYM recurring as the lineage with the largest associated feature set. In cancer cell lines, DPP7 RNA and mutation anchors are most strongly linked to RNA-expression features, especially in PANCREAS, while CRISPR and shRNA rows add functional-dependency signals in SKIN and LARGE_INTESTINE.
