DPP7

Across TCGA cell cohorts, DPP7 mutation is significantly associated with the RNA expression of many other genes, with 285 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible DPP7-associated genes across cancer lineages are MORC1, NXF5, and KRTAP2-1. Each is linked with DPP7 in more than 1 cancer types. Because this analysis shows association rather than direction, both DPP7-to-partner and partner-to-DPP7 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MORC1 grouped by DPP7-low versus DPP7-high in OESOPHAGUS.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (DPP7→partner) and Y-score (partner→DPP7) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OESOPHAGUS	MORC1 →	+0.013	+4.906	<.001	.006	3	1
OESOPHAGUS	NXF5 →	+0.103	+4.906	<.001	.006	3	1
SKIN	KRTAP2-1 →	+0.204	+4.415	<.001	.007	3	1
SKIN	SKOR2 →	+0.347	+4.095	<.001	.009	3	1
SKIN	C7orf77 →	+0.066	+4.415	<.001	.007	3	1
BLOOD_Leukemia	IFNG →	+0.097	+2.889	.005	.002	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 285 associations by consensus.

MORC1 by DPP7 expression — OESOPHAGUS

Explore this box plot interactively →