DPP7

Across TCGA pan-cancer cohorts, DPP7 RNA is linked to patient survival in 27 of 34 cancer types, making it the most broadly survival-associated DPP7 data layer compared with 5 for mutation status and 6 for mass-spec protein.

The strongest signal is observed in colon adenocarcinoma (COAD), where higher DPP7 RNA is associated with worse overall survival. In most high-consensus cancer types, elevated DPP7 expression acts as an unfavorable survival marker, although some lineages such as PAAD and UCEC show a favorable association.

COAD, ACC, and UCS are the cancer types where DPP7 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
COAD	OS	Median	All	0.723	0.871	<.001	168	view →
ACC	DFS	Median	All	0.137	0.717	<.001	108	view →
UCS	OS	Median	IV	0.302	0.817	.002	80	view →
UVM	OS	Quartile	All	0.322	0.781	.001	63	view →
MESO	OS	Median	II,III,IV	0.313	0.732	.003	41	view →
LGG	DFS	Tertile	All	0.278	0.469	<.001	40	view →
PAAD	OS	Tertile	All	0.571	0.244	<.001	37	view →
UCEC	DFS	Quartile	All	0.842	0.676	.005	30	view →
STAD	DFS	Median	All	0.707	0.543	.001	26	view →
READ	OS	Median	II,III,IV	0.797	1.000	.002	18	view →
KIRP	DFS	Median	IV	0.036	0.528	.001	18	view →
CHOL	OS	Median	III,IV	1.000	0.286	.008	16	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 27 lineages.

DPP7–COAD (OS)

Open the COAD breakdown →