DPP7

Across TCGA patient cohorts, DPP7 mutation is significantly associated with the RNA expression of many other genes, with 105 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible DPP7-associated genes across cancer lineages are MIR5590, SNORD115-45, and PRSS3P1. Each is linked with DPP7 in more than 1 cancer types. Because this analysis shows association rather than direction, both DPP7-to-partner and partner-to-DPP7 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MIR5590 grouped by DPP7-low versus DPP7-high in SKCM.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (DPP7→partner) and Y-score (partner→DPP7) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKCM	MIR5590 →	+0.645	+5.513	<.001	.004	3	2
LUSC	SNORD115-45 →	+0.363	+5.191	<.001	.003	3	2
SKCM	PRSS3P1 →	+0.134	+5.436	<.001	.005	3	1
SKCM	SRSF3P2 →	+0.094	+4.979	.003	.009	3	1
SKCM	YWHAZP1 →	+0.069	+5.867	<.001	.003	3	1
SKCM	LINC01974 →	+0.094	+5.292	<.001	.006	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 105 associations by consensus.

MIR5590 by DPP7 expression — SKCM

Explore this box plot interactively →