DPP7

Across TCGA pan-cancer cohorts, DPP7 mass-spec protein is linked to patient survival in 6 of 34 cancer types, making it a survival-associated DPP7 data layer compared with 27 for mass-spec protein and 5 for mutation status.

The strongest signal is observed in clear cell renal cell carcinoma (CCRCC), where higher DPP7 mass-spec protein is associated with better disease-free survival. In most high-consensus cancer types, elevated DPP7 expression acts as an unfavorable survival marker, although some lineages such as CCRCC and PDAC show a favorable association.

CCRCC, GBM, and PDAC are the cancer types where DPP7 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
CCRCC	DFS	Median	All	0.858	0.626	.001	17	view →
GBM	OS	Quartile	All	0.266	0.728	.002	8	view →
PDAC	OS	Quartile	II,III,IV	0.766	0.509	.027	4	view →
UCEC	DFS	Median	All	0.925	0.793	.028	2	view →
LSCC	OS	Quartile	II,III,IV	0.821	1.000	.025	2	view →
HNSC	OS	Quartile	II,III,IV	0.613	0.837	.033	2	view →

Pink = unfavorable, green = favorable. Showing the 6 strongest of 6 lineages.

DPP7–CCRCC (DFS)

Open the CCRCC breakdown →