DPP7

Across TCGA cell cohorts, DPP7 mutation is significantly associated with the mutation status of many other genes, with 5,457 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible DPP7-associated genes across cancer lineages are ZKSCAN5, SBNO2, and AGAP2. Each is linked with DPP7 in more than 4 cancer types. Because this analysis shows association rather than direction, both DPP7-to-partner and partner-to-DPP7 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, ZKSCAN5 grouped by DPP7-low versus DPP7-high in BLOOD_Lymphoma.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (DPP7→partner) and Y-score (partner→DPP7) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Lymphoma	ZKSCAN5 →	+5.014	+5.584	.003	.003	1	5
BLOOD_Leukemia	SBNO2 →	+2.210	+2.478	.005	.005	1	5
LARGE_INTESTINE	AGAP2 →	+2.854	+3.404	<.001	<.001	1	5
SKIN	FBXO38 →	+5.053	+4.239	.007	.007	1	4
SKIN	PACS2 →	+4.053	+4.357	.001	.001	1	4
OVARY	TTC3 →	+2.977	+4.273	.006	.006	1	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,457 associations by consensus.

ZKSCAN5 by DPP7 expression — BLOOD_Lymphoma

Explore this box plot interactively →