zinc finger protein 205Genealiases: RhitH · ZNF210 · Zfp13
Q-omics provides the consensus-scored ZNF205 profile across patient tissues and cancer cell-line models. ZNF205 expression is associated with patient survival in 24 of 34 cancer types, with the highest sampling consensus in UVM. Among the 18 cancer types available for tumor–normal comparison, ZNF205 is differentially expressed in 15, with the highest sampling consensus in KIRP. Additionally, ZNF205 RNA expression shows 17,084 significant gene co-expression associations, with the highest sampling consensus in TGCT. Together, these results highlight UVM, KIRP, and TGCT as cancer lineages where ZNF205 shows reproducible signals across survival, tumor–normal expression, and patient cross-omics analyses.
Every result is evaluated using two consensus scores. Sampling consensus measures how consistently a finding is reproduced within a cancer lineage across different conditions. Lineage consensus measures how broadly the result is shared across cancer types, distinguishing pan-cancer signals from lineage-specific patterns.
Premium analyses for ZNF205 — synthetic lethality, tumor antigen, and pembrolizumab response.
This table summarizes ZNF205 survival associations across molecular data types. ZNF205 RNA expression shows survival associations in the most cancer types (24), followed by mutation status (5) and mass-spec protein abundance (1). The rightmost column indicates the cancer type with the highest sampling consensus for each molecular layer.
This table ranks reproducible ZNF205 RNA expression–survival associations across cancer types. High ZNF205 expression shows unfavorable associations in LIHC, ACC, PRAD and BLCA, but favorable associations in UVM and HNSC. The UVM Kaplan–Meier curve shows clear separation, with the low-expression group declining faster, consistent with the favorable association (log-rank p < 0.001). Together, the overview and detailed table identify UVM as the clearest survival context for ZNF205 RNA expression.
This table summarizes ZNF205 tumor–normal expression differences by data type. RNA shows broader differences across cancer types, with a lineage consensus of 15. The strongest signals are observed in KIRC for RNA.
This table ranks reproducible tumor–normal expression differences for ZNF205. A negative fold-change indicates higher expression in normal tissue than in tumor tissue. ZNF205 shows higher tumor expression in KIRP, KIRC, HNSC, COAD, LIHC and STAD. The KIRP box plot shows higher ZNF205 RNA expression in tumor versus normal tissue (log2 FC = +1.380, t-test p < 0.001).
This table shows molecular features associated with ZNF205 in patient tissues and cancer cell lines. In patient samples, ZNF205 shows the broadest associations at the RNA and protein expression levels, with TGCT recurring as the lineage with the largest associated feature set. In cancer cell lines, ZNF205 RNA and mutation anchors are most strongly linked to RNA-expression features, especially in LARGE_INTESTINE, while CRISPR and shRNA rows add functional-dependency signals in CNS and SKIN.
