ZNF205

Across TCGA patient cohorts, ZNF205 protein abundance is significantly associated with the RNA expression of many other genes, with 470 significant associations in total. GBM shows the largest number of these associations.

The most reproducible ZNF205-associated genes across cancer lineages are AKR7A2P2, CARD10, and FXR1. Each is linked with ZNF205 in more than 1 cancer types. Because this analysis shows association rather than direction, both ZNF205-to-partner and partner-to-ZNF205 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ZNF205 versus AKR7A2P2 in GBM, with a Pearson correlation of 0.58.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF205→partner) and Y-score (partner→ZNF205) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	AKR7A2P2 →	+0.857	+0.387	.004	.009	3	2
BRCA	CARD10 →	-1.674	-0.871	<.001	<.001	3	1
BRCA	FXR1 →	-0.482	-1.002	.008	.004	3	1
BRCA	SSR3 →	-0.625	-0.604	.006	.008	3	1
BRCA	CCNI →	-0.838	-0.656	.003	.003	3	1
BRCA	ATXN10 →	-0.801	-0.722	<.001	.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 470 associations by consensus.

ZNF205 vs AKR7A2P2 — GBM

Explore this scatter interactively →