ZNF205

Across TCGA patient cohorts, ZNF205 RNA expression is significantly associated with the protein abundance of many other proteins, with 12,826 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible ZNF205-associated proteins across cancer lineages are GRB2, SAMSN1_S23, and PLCG2. Each is linked with ZNF205 in more than 4 cancer types. Because this analysis shows association rather than direction, both ZNF205-to-partner and partner-to-ZNF205 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ZNF205 versus GRB2 in CCRCC, with a Pearson correlation of -0.49.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF205→partner) and Y-score (partner→ZNF205) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CCRCC	GRB2 →	-0.311	-0.487	<.001	<.001	3	5
LSCC	SAMSN1_S23 →	-0.603	-0.492	<.001	<.001	3	4
LSCC	PLCG2 →	-0.554	-0.518	<.001	<.001	3	4
GBM	PTPN6 →	-0.450	-0.300	.002	.001	3	4
GBM	SAMSN1 →	-0.573	-0.401	<.001	<.001	3	4
CCRCC	THEMIS2_T593 →	-0.592	-0.496	.002	.002	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 12,826 associations by consensus.

ZNF205 vs GRB2 — CCRCC

Explore this scatter interactively →