ZNF205

Across TCGA cell cohorts, ZNF205 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,804 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible ZNF205-associated GO terms across cancer lineages are Positive regulation of proteasomal ubiquitin-dependent protein catabolic process, Regulation of proteasomal ubiquitin-dependent protein catabolic process, and Calcium-independent cell-matrix adhesion. Each is linked with ZNF205 in more than 13 cancer types. Because this analysis shows association rather than direction, both ZNF205-to-partner and partner-to-ZNF205 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Positive regulation of proteasomal ubiquitin-dependent protein catabolic process grouped by ZNF205-low versus ZNF205-high in SOFT_TISSUE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF205→partner) and Y-score (partner→ZNF205) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SOFT_TISSUE	Positive regulation of proteasomal ubiquitin-dependent protein catabolic process →	+0.068	+0.598	<.001	<.001	3	14
UPPER_AERODIGESTIVE_TRACT	Regulation of proteasomal ubiquitin-dependent protein catabolic process →	+0.064	+0.545	<.001	.005	3	14
BONE	Calcium-independent cell-matrix adhesion →	+0.194	+0.596	<.001	<.001	3	14
OVARY	Regulation of ubiquitin-dependent protein catabolic process →	+0.047	+0.462	<.001	.004	3	14
LIVER	Positive regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway →	+0.157	+0.733	<.001	.003	2	14
URINARY_TRACT	Negative regulation of autophagosome maturation →	+0.124	+0.923	<.001	<.001	3	13

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,804 associations by consensus.

Positive regulation of proteasomal ubiquitin-dependent protein catabolic process by ZNF205 expression — SOFT_TISSUE

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