WSC domain sialate O sulfotransferase 1Genealiases: []
Q-omics provides the consensus-scored WSCD1 profile across patient tissues and cancer cell-line models. WSCD1 expression is associated with patient survival in 29 of 34 cancer types, with the highest sampling consensus in UVM. Among the 18 cancer types available for tumor–normal comparison, WSCD1 is differentially expressed in 12, with the highest sampling consensus in COAD. Additionally, WSCD1 RNA expression shows 17,644 significant gene co-expression associations, with the highest sampling consensus in ACC. Together, these results highlight UVM, COAD, and ACC as cancer lineages where WSCD1 shows reproducible signals across survival, tumor–normal expression, and patient cross-omics analyses.
Every result is evaluated using two consensus scores. Sampling consensus measures how consistently a finding is reproduced within a cancer lineage across different conditions. Lineage consensus measures how broadly the result is shared across cancer types, distinguishing pan-cancer signals from lineage-specific patterns.
Premium analyses for WSCD1 — synthetic lethality, tumor antigen, and pembrolizumab response.
This table summarizes WSCD1 survival associations across molecular data types. WSCD1 RNA expression shows survival associations in the most cancer types (29), followed by mutation status (1) and mass-spec protein abundance (1). The rightmost column indicates the cancer type with the highest sampling consensus for each molecular layer.
This table ranks reproducible WSCD1 RNA expression–survival associations across cancer types. High WSCD1 expression shows unfavorable associations in UVM, BLCA, LUSC and LIHC, but favorable associations in KIRP and HNSC. The UVM Kaplan–Meier curve shows clear separation, with the high-expression group declining faster, consistent with the unfavorable association (log-rank p < 0.001). Together, the overview and detailed table identify UVM as the clearest survival context for WSCD1 RNA expression.
This table summarizes WSCD1 tumor–normal expression differences by data type. RNA shows broader differences across cancer types, with a lineage consensus of 12. The strongest signals are observed in COAD for RNA.
This table ranks reproducible tumor–normal expression differences for WSCD1. A negative fold-change indicates higher expression in normal tissue than in tumor tissue. WSCD1 shows lower tumor expression in COAD, KICH, LUSC, READ and UCEC and higher tumor expression in LIHC. The COAD box plot shows higher WSCD1 RNA expression in normal versus tumor tissue (log2 FC = −2.774, t-test p < 0.001).
This table shows molecular features associated with WSCD1 in patient tissues and cancer cell lines. In patient samples, WSCD1 shows the broadest associations at the RNA and protein expression levels, with ACC recurring as the lineage with the largest associated feature set. In cancer cell lines, WSCD1 RNA and mutation anchors are most strongly linked to RNA-expression features, especially in LUNG_NSCLC_LUAD, while CRISPR and shRNA rows add functional-dependency signals in SOFT_TISSUE and LARGE_INTESTINE.
