WSCD1

Across TCGA pan-cancer cohorts, WSCD1 RNA differs between tumor and matched normal tissue in 12 of 18 cancer types tested, making tumor–normal expression one of WSCD1’s most consistent transcriptional readouts.

The strongest signal is observed in colon adenocarcinoma (COAD), where WSCD1 RNA is repressed in tumor relative to normal tissue. In most cancer types WSCD1 is over-expressed in tumor, although a few such as COAD and KICH show the opposite, repressed pattern.

COAD, KICH, and LUSC are the cancer types where WSCD1 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in WSCD1 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
COAD	Female	II,III,IV	−2.774	<.001	11	view →
KICH	All	III,IV	−1.549	<.001	10	view →
LUSC	Male	II,III,IV	−1.438	<.001	8	view →
READ	Female	All	−2.630	<.001	7	view →
LIHC	Female	II,III,IV	+1.284	<.001	6	view →
UCEC	All	All	−1.163	<.001	6	view →
BRCA	All	III,IV	−1.046	<.001	6	view →
HNSC	Male	All	−0.378	.006	5	view →
KIRC	Male	All	+0.467	.023	3	view →
LUAD	All	All	−0.395	.002	3	view →
CHOL	All	All	+0.832	.007	2	view →
THCA	All	All	+0.229	.009	2	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 12 strongest of 12 lineages.

WSCD1–COAD

Open the COAD breakdown →