WSCD1

Across TCGA patient cohorts, WSCD1 mutation is significantly associated with the RNA expression of many other genes, with 1,937 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible WSCD1-associated genes across cancer lineages are TOMM22P4, RPL30P12, and WDR76. Each is linked with WSCD1 in more than 2 cancer types. Because this analysis shows association rather than direction, both WSCD1-to-partner and partner-to-WSCD1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, TOMM22P4 grouped by WSCD1-low versus WSCD1-high in CESC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (WSCD1→partner) and Y-score (partner→WSCD1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CESC	TOMM22P4 →	+0.144	+6.342	<.001	.001	3	3
LUAD	RPL30P12 →	+0.096	+2.652	<.001	.004	3	3
UCEC	WDR76 →	+0.660	+2.301	<.001	<.001	3	3
BRCA	RNU7-153P →	+0.741	+8.055	<.001	.007	3	2
UCEC	UHRF1 →	+0.826	+1.595	<.001	.003	3	2
UCEC	RNA5SP411 →	+0.897	+1.656	<.001	.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,937 associations by consensus.

TOMM22P4 by WSCD1 expression — CESC

Explore this box plot interactively →