WSCD1

Across TCGA cell cohorts, WSCD1 mutation is significantly associated with the RNA expression of many other genes, with 667 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible WSCD1-associated genes across cancer lineages are ADAM7, OR10R2, and OR10A4. Each is linked with WSCD1 in more than 2 cancer types. Because this analysis shows association rather than direction, both WSCD1-to-partner and partner-to-WSCD1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, ADAM7 grouped by WSCD1-low versus WSCD1-high in BLOOD_Leukemia.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (WSCD1→partner) and Y-score (partner→WSCD1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	ADAM7 →	+0.018	+2.922	<.001	.009	3	3
BLOOD_Leukemia	OR10R2 →	+1.335	+3.288	<.001	<.001	3	3
LIVER	OR10A4 →	+0.023	+3.977	<.001	.006	3	2
LUNG_NSCLC_LUSC	OR1L6 →	+0.080	+4.643	<.001	.008	3	2
LUNG_NSCLC_LUSC	OR1N2 →	+0.116	+4.643	<.001	.008	3	2
BLOOD_Leukemia	NPAP1 →	+0.042	+2.644	.001	.008	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 667 associations by consensus.

ADAM7 by WSCD1 expression — BLOOD_Leukemia

Explore this box plot interactively →