Q-omics provides the consensus-scored WDR88 profile across patient tissues and cancer cell-line models. WDR88 expression is associated with patient survival in 22 of 34 cancer types, with the highest sampling consensus in UCS. Among the 18 cancer types available for tumor–normal comparison, WDR88 is differentially expressed in 10, with the highest sampling consensus in LUAD. Additionally, WDR88 RNA expression shows 20,613 significant gene co-expression associations, with the highest sampling consensus in ACC. Together, these results highlight UCS, LUAD, and ACC as cancer lineages where WDR88 shows reproducible signals across survival, tumor–normal expression, and patient cross-omics analyses.
Every result is evaluated using two consensus scores. Sampling consensus measures how consistently a finding is reproduced within a cancer lineage across different conditions. Lineage consensus measures how broadly the result is shared across cancer types, distinguishing pan-cancer signals from lineage-specific patterns.
Premium analyses for WDR88 — synthetic lethality, tumor antigen, and pembrolizumab response.
This table summarizes WDR88 survival associations across molecular data types. WDR88 RNA expression shows survival associations in the most cancer types (22), followed by mutation status (5). The rightmost column indicates the cancer type with the highest sampling consensus for each molecular layer.
This table ranks reproducible WDR88 RNA expression–survival associations across cancer types. High WDR88 expression shows unfavorable associations in ACC, UCEC and KICH, but favorable associations in UCS, PAAD and READ. The UCS Kaplan–Meier curve shows clear separation, with the low-expression group declining faster, consistent with the favorable association (log-rank p < 0.001). Together, the overview and detailed table identify UCS as the clearest survival context for WDR88 RNA expression.
This table summarizes WDR88 tumor–normal expression differences by data type. RNA shows broader differences across cancer types, with a lineage consensus of 10. The strongest signals are observed in LUAD for RNA.
This table ranks reproducible tumor–normal expression differences for WDR88. A negative fold-change indicates higher expression in normal tissue than in tumor tissue. WDR88 shows lower tumor expression in KICH and higher tumor expression in LUAD, LIHC, CHOL, BLCA and LUSC. The LUAD box plot shows higher WDR88 RNA expression in tumor versus normal tissue (log2 FC = +0.847, t-test p < 0.001).
This table shows molecular features associated with WDR88 in patient tissues and cancer cell lines. In patient samples, WDR88 shows the broadest associations at the RNA and protein expression levels, with ACC recurring as the lineage with the largest associated feature set. In cancer cell lines, WDR88 RNA and mutation anchors are most strongly linked to RNA-expression features, especially in CNS, while CRISPR and shRNA rows add functional-dependency signals in UPPER_AERODIGESTIVE_TRACT and BLOOD_Leukemia.
