WDR88

Across TCGA patient cohorts, WDR88 mutation is significantly associated with the RNA expression of many other genes, with 1,671 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible WDR88-associated genes across cancer lineages are SAR1B, AIM2, and C4orf3. Each is linked with WDR88 in more than 2 cancer types. Because this analysis shows association rather than direction, both WDR88-to-partner and partner-to-WDR88 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, SAR1B grouped by WDR88-low versus WDR88-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (WDR88→partner) and Y-score (partner→WDR88) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	SAR1B →	+0.423	+1.807	<.001	.004	3	3
UCEC	AIM2 →	+0.512	+2.447	.007	.001	3	3
UCEC	C4orf3 →	+0.420	+1.839	.007	.002	3	3
UCEC	ELAC2 →	+0.406	+3.000	<.001	<.001	3	3
UCEC	UFD1 →	+0.452	+3.272	<.001	<.001	3	3
UCEC	TIPIN →	+0.448	+2.158	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,671 associations by consensus.

SAR1B by WDR88 expression — UCEC

Explore this box plot interactively →