WDR88

Across TCGA pan-cancer cohorts, WDR88 RNA is linked to patient survival in 22 of 34 cancer types, making it the most broadly survival-associated WDR88 data layer compared with 5 for mutation status.

The strongest signal is observed in uterine carcinosarcoma (UCS), where higher WDR88 RNA is associated with better disease-free survival. In most high-consensus cancer types, elevated WDR88 expression acts as an unfavorable survival marker, although some lineages such as UCS and PAAD show a favorable association.

UCS, PAAD, and ACC are the cancer types where WDR88 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
UCS	DFS	Tertile	II,III,IV	0.569	0.178	<.001	90	view →
PAAD	OS	Median	All	0.510	0.295	<.001	76	view →
ACC	DFS	Median	All	0.401	0.748	<.001	59	view →
UCEC	DFS	Tertile	All	0.561	0.751	<.001	58	view →
READ	DFS	Quartile	All	0.745	0.193	.003	49	view →
KICH	OS	Quartile	All	0.714	1.000	.006	32	view →
MESO	OS	Tertile	II,III,IV	0.737	0.299	.008	21	view →
THCA	DFS	Quartile	II,III,IV	0.755	0.904	.021	16	view →
KIRC	DFS	Quartile	II,III,IV	0.338	0.619	.014	13	view →
LGG	OS	Tertile	All	0.736	0.905	.003	10	view →
SCLC	DFS	Quartile	All	0.516	0.211	.009	9	view →
CHOL	DFS	Median	All	0.650	0.232	.011	9	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 22 lineages.

WDR88–UCS (DFS)

Open the UCS breakdown →