WDR88

Across TCGA cell cohorts, WDR88 mutation is significantly associated with the RNA expression of many other genes, with 10 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible WDR88-associated genes across cancer lineages are OPN1MW, C20orf85, and IL22. Each is linked with WDR88 in more than 1 cancer types. Because this analysis shows association rather than direction, both WDR88-to-partner and partner-to-WDR88 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, OPN1MW grouped by WDR88-low versus WDR88-high in SKIN.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (WDR88→partner) and Y-score (partner→WDR88) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKIN	OPN1MW →	+0.016	+4.415	.001	.007	3	1
BLOOD_Leukemia	C20orf85 →	+0.049	+5.969	<.001	.001	3	1
BLOOD_Leukemia	IL22 →	+0.050	+6.569	<.001	<.001	3	1
BLOOD_Leukemia	LRRTM3 →	+0.006	+5.539	<.001	.003	3	1
BLOOD_Leukemia	OR2A5 →	+0.021	+4.922	<.001	.009	3	1
LARGE_INTESTINE	GSG1L2 →	+0.011	+3.700	<.001	.009	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 10 associations by consensus.

OPN1MW by WDR88 expression — SKIN

Explore this box plot interactively →