Q-omics provides the consensus-scored UBTD2 profile across patient tissues and cancer cell-line models. UBTD2 expression is associated with patient survival in 24 of 34 cancer types, with the highest sampling consensus in MESO. Among the 18 cancer types available for tumor–normal comparison, UBTD2 is differentially expressed in 12, with the highest sampling consensus in HNSC. Additionally, UBTD2 RNA expression shows 20,240 significant gene co-expression associations, with the highest sampling consensus in ACC. Together, these results highlight MESO, HNSC, and ACC as cancer lineages where UBTD2 shows reproducible signals across survival, tumor–normal expression, and patient cross-omics analyses.
Every result is evaluated using two consensus scores. Sampling consensus measures how consistently a finding is reproduced within a cancer lineage across different conditions. Lineage consensus measures how broadly the result is shared across cancer types, distinguishing pan-cancer signals from lineage-specific patterns.
Premium analyses for UBTD2 — synthetic lethality, tumor antigen, and pembrolizumab response.
This table summarizes UBTD2 survival associations across molecular data types. UBTD2 RNA expression shows survival associations in the most cancer types (24), followed by mutation status (4) and mass-spec protein abundance (4). The rightmost column indicates the cancer type with the highest sampling consensus for each molecular layer.
This table ranks reproducible UBTD2 RNA expression–survival associations across cancer types. High UBTD2 expression shows unfavorable associations in MESO, LIHC and STAD, but favorable associations in UCS, KIRC and COAD. The MESO Kaplan–Meier curve shows clear separation, with the high-expression group declining faster, consistent with the unfavorable association (log-rank p < 0.001). Together, the overview and detailed table identify MESO as the clearest survival context for UBTD2 RNA expression.
This table summarizes UBTD2 tumor–normal expression differences by data type. RNA shows broader differences across cancer types, with a lineage consensus of 12, while mass-spec protein shows differences in 5. The strongest signals are observed in HNSC for RNA and LSCC for protein.
This table ranks reproducible tumor–normal expression differences for UBTD2. A negative fold-change indicates higher expression in normal tissue than in tumor tissue. UBTD2 shows lower tumor expression in KICH and higher tumor expression in HNSC, LIHC, BRCA, CHOL and LUAD. The HNSC box plot shows higher UBTD2 RNA expression in tumor versus normal tissue (log2 FC = +1.226, t-test p < 0.001).
This table shows molecular features associated with UBTD2 in patient tissues and cancer cell lines. In patient samples, UBTD2 shows the broadest associations at the RNA and protein expression levels, with ACC recurring as the lineage with the largest associated feature set. In cancer cell lines, UBTD2 RNA and mutation anchors are most strongly linked to RNA-expression features, especially in PANCREAS, while CRISPR and shRNA rows add functional-dependency signals in KIDNEY and BLOOD_Leukemia.
