UBTD2

mutation — cross-omics
Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, UBTD2 mutation is significantly associated with the RNA expression of many other genes, with 1,270 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible UBTD2-associated genes across cancer lineages are MIR7702, RNU6-225P, and LINC01943. Each is linked with UBTD2 in more than 1 cancer types. Because this analysis shows association rather than direction, both UBTD2-to-partner and partner-to-UBTD2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MIR7702 grouped by UBTD2-low versus UBTD2-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (UBTD2→partner) and Y-score (partner→UBTD2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
UCECMIR7702 →+0.191+3.973<.001.00632
BLCARNU6-225P →+0.352+7.640<.001.00931
UCECLINC01943 →+0.522+2.447<.001.00131
UCECARRDC3-AS1 →+0.243+2.659.005.00531
UCECDHRS11 →+0.698+3.098<.001<.00131
UCECMICALL1 →+0.579+3.191.001.00931
Each partner links to its Q-omics profile. Showing the 6 strongest of 1,270 associations by consensus.

MIR7702 by UBTD2 expression — UCEC

Box plot of MIR7702 in UBTD2-low vs UBTD2-high samples in UCEC.

Explore this box plot interactively →

Exploration