Q-omics provides the consensus-scored TEX47 profile across patient tissues and cancer cell-line models. TEX47 expression is associated with patient survival in 16 of 34 cancer types, with the highest sampling consensus in MESO. Among the 18 cancer types available for tumor–normal comparison, TEX47 is differentially expressed in 4, with the highest sampling consensus in THCA. Additionally, TEX47 RNA expression shows 6,519 significant gene co-expression associations, with the highest sampling consensus in BLCA. Together, these results highlight MESO, THCA, and BLCA as cancer lineages where TEX47 shows reproducible signals across survival, tumor–normal expression, and patient cross-omics analyses.
Every result is evaluated using two consensus scores. Sampling consensus measures how consistently a finding is reproduced within a cancer lineage across different conditions. Lineage consensus measures how broadly the result is shared across cancer types, distinguishing pan-cancer signals from lineage-specific patterns.
Premium analyses for TEX47 — synthetic lethality, tumor antigen, and pembrolizumab response.
This table summarizes TEX47 survival associations across molecular data types. TEX47 RNA expression shows survival associations in the most cancer types (16), followed by mutation status (4). The rightmost column indicates the cancer type with the highest sampling consensus for each molecular layer.
This table ranks reproducible TEX47 RNA expression–survival associations across cancer types. High TEX47 expression shows unfavorable associations in MESO, HNSC, SKCM, STAD and COAD, but favorable associations in BLCA. The MESO Kaplan–Meier curve shows clear separation, with the high-expression group declining faster, consistent with the unfavorable association (log-rank p < 0.001). Together, the overview and detailed table identify MESO as the clearest survival context for TEX47 RNA expression.
This table summarizes TEX47 tumor–normal expression differences by data type. RNA shows broader differences across cancer types, with a lineage consensus of 4. The strongest signals are observed in THCA for RNA.
This table ranks reproducible tumor–normal expression differences for TEX47. A negative fold-change indicates higher expression in normal tissue than in tumor tissue. TEX47 shows lower tumor expression in THCA, KIRC and KICH and higher tumor expression in LUAD. The THCA box plot shows higher TEX47 RNA expression in normal versus tumor tissue (log2 FC = −0.470, t-test p < 0.001).
This table shows molecular features associated with TEX47 in patient tissues and cancer cell lines. In patient samples, TEX47 shows the broadest associations at the RNA and protein expression levels, with BLCA recurring as the lineage with the largest associated feature set. In cancer cell lines, TEX47 RNA and mutation anchors are most strongly linked to RNA-expression features, especially in OVARY, while CRISPR and shRNA rows add functional-dependency signals in UPPER_AERODIGESTIVE_TRACT and LUNG_SCLC.
