TEX47

Across TCGA cell cohorts, TEX47 mutation is significantly associated with the mutation status of many other genes, with 657 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible TEX47-associated genes across cancer lineages are BRD7, CASK, and MTMR10. Each is linked with TEX47 in more than 2 cancer types. Because this analysis shows association rather than direction, both TEX47-to-partner and partner-to-TEX47 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, BRD7 grouped by TEX47-low versus TEX47-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TEX47→partner) and Y-score (partner→TEX47) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	BRD7 →	+2.744	+4.321	.002	.002	1	3
LARGE_INTESTINE	CASK →	+2.284	+3.925	.005	.005	1	3
LARGE_INTESTINE	MTMR10 →	+3.744	+4.044	.003	.003	1	2
LARGE_INTESTINE	SLFN11 →	+3.329	+3.799	.005	.005	1	2
LARGE_INTESTINE	KCNA2 →	+3.329	+3.799	.005	.005	1	2
LARGE_INTESTINE	RAB39A →	+4.329	+4.329	.001	.001	1	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 657 associations by consensus.

BRD7 by TEX47 expression — LARGE_INTESTINE

Explore this box plot interactively →