TEX47

Across TCGA pan-cancer cohorts, TEX47 RNA is linked to patient survival in 16 of 34 cancer types, making it the most broadly survival-associated TEX47 data layer compared with 4 for mutation status.

The strongest signal is observed in mesothelioma (MESO), where higher TEX47 RNA is associated with worse overall survival. In most high-consensus cancer types, elevated TEX47 expression acts as an unfavorable survival marker, although some lineages such as BLCA and ESCA show a favorable association.

MESO, HNSC, and SKCM are the cancer types where TEX47 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
MESO	OS	Tertile	IV	0.036	0.602	<.001	72	view →
HNSC	OS	Tertile	II,III,IV	0.225	0.725	<.001	72	view →
SKCM	DFS	Tertile	All	0.109	0.217	.008	54	view →
STAD	DFS	Tertile	All	0.428	0.732	.002	42	view →
COAD	OS	Tertile	IV	0.045	0.659	<.001	36	view →
BLCA	OS	Tertile	IV	0.646	0.433	.034	33	view →
KIRC	DFS	Tertile	III,IV	0.269	0.492	.021	21	view →
ESCA	OS	Tertile	III,IV	0.897	0.369	.015	18	view →
LUSC	DFS	Tertile	II,III,IV	0.911	0.567	.020	15	view →
UCEC	OS	Tertile	II,III,IV	1.000	0.515	.047	12	view →
LIHC	DFS	Tertile	All	0.221	0.559	.011	9	view →
ACC	OS	Tertile	All	0.143	0.704	.026	9	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 16 lineages.

TEX47–MESO (OS)

Open the MESO breakdown →