TEX47

Across TCGA cell cohorts, TEX47 RNA expression is significantly associated with the mutation status of many other genes, with 32 significant associations in total. LUNG_SCLC shows the largest number of these associations.

The most reproducible TEX47-associated genes across cancer lineages are DNAJA2, EPB41L2, and COL4A5. Each is linked with TEX47 in more than 1 cancer types. Because this analysis shows association rather than direction, both TEX47-to-partner and partner-to-TEX47 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, DNAJA2 grouped by TEX47-low versus TEX47-high in LUNG_SCLC.

RNA expression associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TEX47→partner) and Y-score (partner→TEX47) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_SCLC	DNAJA2 →	+4.044	+0.285	.009	<.001	3	1
LUNG_SCLC	EPB41L2 →	+4.044	+0.160	.009	.002	3	1
KIDNEY	COL4A5 →	+5.000	+0.020	.005	<.001	3	1
KIDNEY	ARVCF →	+5.000	+0.020	.005	<.001	3	1
LARGE_INTESTINE	EPOR →	+5.415	+0.032	.004	<.001	3	1
LARGE_INTESTINE	ADAMTSL2 →	+5.415	+0.032	.004	<.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 32 associations by consensus.

DNAJA2 by TEX47 expression — LUNG_SCLC

Explore this box plot interactively →