TEX47

Across TCGA cell cohorts, TEX47 mutation is significantly associated with the RNA expression of many other genes, with 10 significant associations in total. STOMACH shows the largest number of these associations.

The most reproducible TEX47-associated genes across cancer lineages are TBL1Y, OR1L1, and OBP2A. Each is linked with TEX47 in more than 1 cancer types. Because this analysis shows association rather than direction, both TEX47-to-partner and partner-to-TEX47 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, TBL1Y grouped by TEX47-low versus TEX47-high in LUNG_NSCLC_LUSC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TEX47→partner) and Y-score (partner→TEX47) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUSC	TBL1Y →	+0.053	+4.643	<.001	.008	3	1
LUNG_SCLC	OR1L1 →	+0.052	+5.029	<.001	.006	3	1
STOMACH	OBP2A →	+0.312	+4.432	<.001	.003	3	1
STOMACH	SSTR4 →	+0.065	+4.129	<.001	.007	3	1
STOMACH	OR2V2 →	+0.018	+4.432	<.001	.003	3	1
STOMACH	OR10G7 →	+0.067	+4.285	<.001	.007	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 10 associations by consensus.

TBL1Y by TEX47 expression — LUNG_NSCLC_LUSC

Explore this box plot interactively →