arginine and serine rich protein 1Genealiases: C1orf63 · NPD014
Q-omics provides the consensus-scored RSRP1 profile across patient tissues and cancer cell-line models. RSRP1 expression is associated with patient survival in 23 of 34 cancer types, with the highest sampling consensus in BLCA. Among the 18 cancer types available for tumor–normal comparison, RSRP1 is differentially expressed in 10, with the highest sampling consensus in BLCA. Additionally, RSRP1 RNA expression shows 18,946 significant gene co-expression associations, with the highest sampling consensus in UVM. Together, these results highlight BLCA, and UVM as cancer lineages where RSRP1 shows reproducible signals across survival, tumor–normal expression, and patient cross-omics analyses.
Every result is evaluated using two consensus scores. Sampling consensus measures how consistently a finding is reproduced within a cancer lineage across different conditions. Lineage consensus measures how broadly the result is shared across cancer types, distinguishing pan-cancer signals from lineage-specific patterns.
Premium analyses for RSRP1 — synthetic lethality, tumor antigen, and pembrolizumab response.
This table summarizes RSRP1 survival associations across molecular data types. RSRP1 RNA expression shows survival associations in the most cancer types (23), followed by mutation status (2) and mass-spec protein abundance (2). The rightmost column indicates the cancer type with the highest sampling consensus for each molecular layer.
This table ranks reproducible RSRP1 RNA expression–survival associations across cancer types. High RSRP1 expression shows unfavorable associations in KIRC, ACC, KICH, LGG and LIHC, but favorable associations in BLCA. The BLCA Kaplan–Meier curve shows clear separation, with the low-expression group declining faster, consistent with the favorable association (log-rank p < 0.001). Together, the overview and detailed table identify BLCA as the clearest survival context for RSRP1 RNA expression.
This table summarizes RSRP1 tumor–normal expression differences by data type. RNA shows broader differences across cancer types, with a lineage consensus of 10, while mass-spec protein shows differences in 1. The strongest signals are observed in BLCA for RNA and LSCC for protein.
This table ranks reproducible tumor–normal expression differences for RSRP1. A negative fold-change indicates higher expression in normal tissue than in tumor tissue. RSRP1 shows lower tumor expression in KICH and BRCA and higher tumor expression in BLCA, LIHC, COAD and THCA. The BLCA box plot shows higher RSRP1 RNA expression in tumor versus normal tissue (log2 FC = +1.217, t-test p < 0.001).
This table shows molecular features associated with RSRP1 in patient tissues and cancer cell lines. In patient samples, RSRP1 shows the broadest associations at the RNA and protein expression levels, with UVM recurring as the lineage with the largest associated feature set. In cancer cell lines, RSRP1 RNA and mutation anchors are most strongly linked to RNA-expression features, especially in BLOOD_Lymphoma, while CRISPR and shRNA rows add functional-dependency signals in URINARY_TRACT and SOFT_TISSUE.
